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Position Summary We're seeking an Associate Director, IT Infrastructure to lead and transform our scientific computing environment in support of our cutting-edge gene therapy research. This senior leadership position will drive the strategy and execution of research computing initiatives, working in close partnership with our Bioinformatics, AI/ML, and Global IT Infrastructure teams. The role focuses specifically on advancing our scientific computing capabilities through operational excellence, while ensuring our research teams can maximize the value of our high-performance computing investments.   As a key member of the technology leadership team, this position will be responsible for the day-to-day operations and strategic evolution of our research computing environment. The successful candidate will combine deep technical expertise in scientific computing with strong business acumen to deliver innovative solutions that accelerate our research mission. While Global IT Infrastructure maintains our enterprise technology foundation, this role focuses exclusively on the specialized computing needs of our scientific teams, including high-performance computing, GPU-accelerated workflows, and research data management.   Job Responsibilities Serve as the primary local IT Infrastructure contact for Edinburgh's Bioinformatics and AI/ML teams Manage and optimize scientific computing infrastructure, including GPU clusters, high-performance storage systems, and virtualized environments Collaborate with global IT teams to ensure infrastructure alignment with scientific computing needs Lead technical planning and implementation of infrastructure improvements Provide technical guidance on architecture decisions affecting scientific workflows Manage and optimize WEKA storage systems and VSphere virtual environments Support Linux-based scientific computing environments, leveraging managed services as appropriate Implement and maintain monitoring solutions for complex computing environments Participate in capacity planning and performance optimization initiatives Drive infrastructure automation and continuous improvement Manage relationships with vendors and technical partners   Vendor & Contract Management: Manage third-party Linux support contract and contractor relationships Define and monitor service level agreements Ensure contractor compliance with company security policies Review and approve contractor work Manage vendor performance and escalations   Security & Compliance: Act as primary point of contact for parent company security audits Develop and maintain security compliance documentation Coordinate and respond to penetration testing activities Implement security recommendations and remediation plans Ensure infrastructure meets corporate security standards Participate in security incident response planning   Business Continuity: Lead disaster recovery planning for scientific computing infrastructure Coordinate and execute DR testing Maintain DR documentation and procedures Develop and maintain business continuity plans Ensure RPO/RTO objectives are met   Financial Planning & Technical Debt: Develop long-term capital planning for infrastructure Manage infrastructure budget and forecasting for AskBio European locations Identify and track technical debt Create remediation plans for technical debt Provide cost-benefit analysis for infrastructure investments Manage infrastructure lifecycle planning Develop business cases for infrastructure improvements    Key Competencies:   Technical: Infrastructure architecture and design Performance optimization Problem-solving and troubleshooting Security best practices Technical documentation   Business & Management: Contract negotiation and management Budget planning and control Risk management Audit response and compliance Strategic planning Vendor management Cost-benefit analysis   Interpersonal: Strong communication skills Stakeholder management Team collaboration Conflict resolution Customer service orientation Ability to bridge technical and scientific domains   Leadership: Technical leadership Project management Mentoring and knowledge transfer Change management Strategic thinking   Impact Metrics: Success in this role will be measured by: Infrastructure stability and performance improvements Stakeholder satisfaction levels Project delivery effectiveness Technical problem resolution metrics Team collaboration effectiveness Innovation and process improvements   Note: This position requires occasional travel to other company locations and may require some out-of-hours support during critical maintenance windows or emergencies.   This role represents a critical position in our organization, bridging technical expertise with scientific computing needs while fostering strong working relationships between global teams.   ​Minimum Requirements Bachelor's degree in Computer Science, Engineering, or related field 8+ years of experience in infrastructure engineering roles Experience with high-performance computing environments Proven experience supporting GPU-accelerated computing environments Strong understanding of storage systems and networking Experience with infrastructure monitoring and optimization tools Demonstrated ability to work with scientific computing workflows Experience managing vendor relationships and contracts Knowledge of IT security and compliance requirements Experience with disaster recovery planning and testing Understanding of IT financial planning and budgeting Experience with audit responses and compliance documentation Strong experience with Linux administration and engineering Extensive knowledge of virtualization technologies, particularly VSphere   Preferred Education, Experience and Skills Experience with WEKA storage systems Knowledge of AI/ML infrastructure requirements Experience supporting bioinformatics workflows Familiarity with container technologies (Docker, Kubernetes) Experience with infrastructure automation tools Understanding of scientific computing software and frameworks Previous experience in biotech or pharmaceutical industries Experience with cloud platforms (AWS, Azure) ITIL certification Security certifications (CISSP, CISM, or similar) Experience with GxP compliance Experience with pharmaceutical industry regulations Previous experience managing technical debt in regulated environments

Role and Responsibilities This is an excellent opportunity for a capable web developer who enjoys owning features end-to-end in a modern, forward-thinking financial services business. We have our own proprietary applications, both back-office solutions as well as client facing. You will work on multiple projects including continuing to enhance our own CRM solution, migrating legacy WebForms functionality to clean services and a modern UI. You’ll work in a fast-paced, dynamic environment; you will not be a “cog in the machine.” You’ll be involved in every aspect of delivery - from requirements and design, to development, testing, deployment, documentation, and support, with a strong focus on scalability and maintainability. We are an extremely fast-growing business and as such, you will be required to adapt quickly to changes and business requirements. You must have a willingness to learn and adapt quickly in order to satisfy changes to business requirements. The job role will consist of the below responsibilities: Development CRM (WebForms/.NET/TSQL/BPM): Configure and extend our proprietary CRM using TSQL, BPM/workflow tools and C# Modernisation: Incremental modernisation of legacy applications using strangler pattern Client facing applications: Develop our customer self service portal and other front-end applications utilising React/Typescript and .NET 9 Web API Azure implementation: Assist in administering our cloud infrastructure (App Service/Functions, Azure SQL, Storage, Key Vault with Managed Identity, App Configuration, Private Endpoints, Application Insights) Quality/pipelines: Contribute to and set up CI/CD pipelines, unit/integration tests where required Testing: Conduct thorough testing and peer review of work items Data Analysis (SQL Server/TSQL) Write performance conscious, SARGable queries and implement appropriate indexing Monitor and apply performance fixes and other DB management tasks in Azure SQL Server hosted DB Technical Documentation Produce documentation for requirement gathering, code architecture and training guides Contribute to due diligence and penetration test readiness packs (architecture diagrams, data flows and controls) Support Triage and resolve support tickets relating to in-house applications from employees Support customer facing applications and address incidents utilising Azure Application Insights and application logs to identify and resolve issues Requirement Gathering: Communicate with stakeholders to establish clear problem statements and requirements Translate requirements into technical solutions with a focus on extendibility and minimising technical debt, considering future changes Accountability and Working Relationships Part of a small, highly motivated and productive development team Partners closely with CTO (hands on) Collaborates and in direct communication with operations, advice, compliance and administration teams to deliver appropriate solutions Accountable for delivering projects on time and to specification Working Environment and Hours: Office based in Doncaster (remote working can be available on occasions where required, however office based is preferred) Monday to Friday, 09:00-17:30. Hours can be flexible within reason and to ensure delivery of key milestones Benefits Competitive salary (dependent on experience) 24 days annual leave (plus bank holidays) Pension scheme Can be very flexible on working hours dependent on requirements and ensuring delivery of key milestones Opportunity to own meaningful projects end-to-end in a growing, entrepreneurial business Big opportunity to learn new emerging technologies (particularly AI), while at work Skills – Essential C# .NET (6+): Dependency Injection, Web API Working knowledge and experience of legacy .NET Framework 4.x and WebForms Microsoft SQL Server: Strong T-SQL, SARGability and indexing, performance tuning mindset TypeScript/React: Component reusability, state management Auth and Security: Securing SPA/APIs using flows such as OAuth2/OIDC Microsoft Azure (hands-on): VMs, App Service, Functions/Logic Apps, Azure SQL, Storage, Key Vault (Managed Identity), App Configuration, Application Insights; basic networking/private endpoints/DNS concepts CI/CD: GitHub Actions/Azure DevOps; environment-aware configuration and secret management Skills – Desirable Firebase: authentication, hosting, functions, Firestore React Native and building mobile apps Exposure to Azure AI Foundry or other AI orchestration (prompting/evaluation/workflows) Experience migrating legacy codebases to modern architecture Using Entra ID for authentication (OAuth2 Flow) Azure infrastructure set up including VNET/Private endpoint and DNS management and setting up secure landing zones Twilio API Industry knowledge of Financial services particularly retirement and custodial platforms Knowledge and experience working with the Seccl API Development Path Candidates slightly lighter in one area (like React or Azure) but strong in WebForms + C# + SQL and motivated to learn will be considered, provided they can show understanding of fundamentals and are willing to learn quickly. Comfortable operating across legacy and modern stacks in the same day. Job Type: Full-time Benefits:   Company events Company pension Free parking On-site parking   Ability to commute/relocate:   Doncaster DN4 5NL: reliably commute or plan to relocate before starting work (preferred)   Work Location: In person

3rd Line ICT Support Engineer Salary £50,000* per annum - *the salary includes a market supplement (reviewed annually), base pay band Grade F (£36,124 - £40,476). Based at Derbyshire Fire & Rescue Service Headquarters, Butterley Hall, Ripley, Derbyshire. Agile working arrangements can be discussed with the successful candidate. Derbyshire Fire & Rescue Service is looking to recruit a 3rd Line ICT Support Engineer to assist in ensuring the IT infrastructure, Systems and Data are fit for purpose, secure, subject to continual improvement, and that our end-users are provided excellent support and customer service. As a 3rd Line ICT Support Engineer, you will be responsible for providing support for a range of infrastructure technologies, including networking, switches, firewalls, windows servers, end user systems, station end equipment (mobile devices, pagers, alerters), supporting system administrators and troubleshooting issues across the ICT estate. Known for your customer-focused approach, you will support the Service’s users, assisting in diagnosing and solving issues across our ICT infrastructure, systems and data including physical, virtual and cloud environments. You will assist the ICT Service Delivery Manager in providing excellent support to business-critical applications, requiring you to possess excellent time management and organisational skills, communications skills, alongside a broad technical knowledge.  You will be able to demonstrate: Excellent ICT Problem solving in a mission critical environment. A strong understanding of networking technologies, including switches & firewalls. A strong understanding of Microsoft Windows operating system technologies. A strong understanding of virtualised server and desktop provision. A strong understanding of cloud-based infrastructure. An excellent all-round ICT support understanding and working as part of a busy technical team. Can we count on you to deliver a customer-focused service that is consistent, reliable and focused on excellence? There will be a requirement for some travel for which a pool car will be provided. The normal working week is 37 hours, usually worked Monday to Friday, however you may occasionally need to work beyond normal office hours, evenings and weekends as required.  The postholder will also be required to provide rota cover on the Recall to Duty Scheme. In return we offer; Flexible working hours. Family friendly policies. Annual Leave entitlement of 27 days, increasing to 32 days after 5 years’ service. Free, secure on-site car parking. Health & wellbeing services, including free access to gyms at Derbyshire Fire & Rescue Service locations. Employee discount scheme (Boost). Employee support networks. Enhanced Maternity Pay (subject to meeting eligibility criteria). Occupational Sick Pay subject to length of service, increasing up to 6 months’ full & 6 months’ half after 5 years’ service. Ongoing training and development opportunities. Eligibility to join the Local Government Pension Scheme with generous employer contributions. Eligibility to join Additional Voluntary Contributions (AVC) offering highly beneficial tax advantages. We are committed to equality and fairness at work.  Applications are encouraged from all diverse communities. Under the Disability Confident scheme, we will offer an interview to a fair and proportionate number of applicants with a disability that meet the essential criteria for the role. We are committed to safeguarding and promoting the welfare of Adults, Children and Young People. Our recruitment and selection procedures reflect this, and all staff are expected to share this commitment. Police security vetting procedures at the appropriate level will be requested for the successful applicant. Please note that, due to the nature of security checks undertaken, applicants must have 3 years continuous residency in the UK up to the date of the application and Home Office approval for indefinite leave to remain within the UK.   To apply please visit: https://www.jobtrain.co.uk/derbyshirefire/Job/JobDetail?JobId=931   The closing date for completed applications is midnight on 20.04.2025 . Interviews will be held in the week commencing 12.05.2025.   For an informal chat regarding the role please contact the ICT Service Delivery Manager Brett Clements on 01773 305344 or email bclements@derbys-fire.gov.uk. If you have a disability and need assistance completing the application form, please contact the Service Centre on 01773 305441.    

Why work with Inuvi At Inuvi, our mission is to foster a work environment where innovation, collaboration, and personal growth are at the forefront. We believe in the power of diverse perspectives and strive to create a culture where every team member feels valued and empowered to contribute their unique ideas. Working with us means being part of a dynamic team that is passionate about making a positive impact on our customers and the industry.   Introducing Inuvi’s IT team At Inuvi, our IT team is dedicated to ensuring the seamless operation and continuous improvement of our systems. The team is responsible for the support, deployment, automation, and maintenance of our infrastructure, ensuring its availability, performance, scalability, and security. Our IT professionals bring a wealth of experience from various backgrounds and work collaboratively with other departments to tackle complex challenges. With a strong focus on innovation and efficiency, the IT team plays a crucial role in driving Inuvi's success and delivering exceptional value to our customers.   What we are looking for We are looking for an IT Infrastructure Analyst to be responsible for the support, deployment, automation and maintenance of our systems whilst ensuring their availability, performance scalability and security.  You must have proven “hands on” experience in a similar role with a good understanding of IT Infrastructure both on premise and in the cloud; which includes a good understanding of DevOps engineering practices. As a small team our roles are broad which will enable your involvement in a range of technologies and projects and foster opportunities for your personal growth. You must be able to demonstrate real world experience of IT infrastructure both on-premise and in the AWS cloud which includes: Good working knowledge of on-premises server infrastructure including Hyper-V servers, storage arrays, switches and firewalls. An excellent understanding of AWS, and a wealth of practical hands-on real-world experience using the core services (EC2, CloudWatch, IAM, RDS, S3 etc at a minimum) An excellent understanding of networking principles and technologies (subnets, VLANs and routing) A good understanding of development pipelines and the technologies used to implement them in AWS and/or Azure Experience using Docker containers Good working knowledge of Linux and Windows server administration and support Experience with JIRA, Bitbucket/Git Proficiency at scripting (especially PowerShell) A good understanding of database technologies (MySQL in particular) and experience administering them Strong interpersonal and communication skills with an ability to produce documentation to a high standard Ability to troubleshoot in a logical manner with a pro-active approach, spot potential problems, escalate and react when necessary Ability to deal competently with pressure and be able to prioritise workload Effective collaboration with other members of the IT team and wider business   In return, we will ensure you have: Very competitive salary with annual salary reviews 25 days holiday a year (plus bank holidays) for some well-deserved time off Opportunity to purchase an additional holiday each year Pension contributions of 5% Annual wellbeing health check Health Shield cash plan Death in service benefit Cycle to work scheme What happens next After receiving your application, our team will review it and inform you of the next steps. If you are selected for the next stage, we will schedule an introductory Teams call to provide more information about our company, learn more about you, and understand your expectations. This will be an opportunity for you to ask any questions you may have. Please choose a time when you can be in a quiet place without distractions. Depending on the outcome of the call, the following stage will involve a face-to-face interview at our Wokingham office, which will also include practical technical questions. We understand the effort required to apply for a new job and value your time. We look forward to reviewing your application. This is an office-based role in Wokingham, Berkshire (RG41) and therefore candidates need to be located within a commutable distance to the office.  We will not consider candidates who need to relocate to be nearer the office.